Session Index

A sandwich-type immunoassay for simultaneous detection of low-concentration of cardiac troponin I (cTnI) and N-terminal pro-brain natriuretic peptide (NT-proBNP) was developed by integrating two types of upconversion nanoparticles (UCNPs) with a low refractive index resonant waveguide grating (RWG). Under resonant excitation, the local electric field is enhanced atop the RWG leading to extremely high intensity of UCL, resulting in improving the detection sensitivity of the immuno-biosensor. The limit of detection of the biosensor is 0.76 fg·mL-1 for cTnI, and 0.98 fg·mL-1 for NT-proBNP, much lower than the serum cut-off value of 30 pg·mL-1 for cTnI and 450 pg·mL-1 for NT-proBNP.

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Traditional Shack-Hartmann wavefront sensors are typically constructed with bulky components, resulting in their weight and the occurrence of chromatic aberration. In contrast, utilizing a metalens not only reduces the physical size but also eliminates chromatic aberration, making it suitable for multi-wavelength wavefront sensing. In this work, we developed a multi-wavelength metalens capable of simultaneously operating at three different wavelengths for compact wavefront sensor application.

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In this study, we designed a split-ring resonator metamaterial for gas sensing of the nitric oxide (NO) in the terahertz frequency range (resonating at 0.257 THz). To further enhance gas absorption, a thin film composed of ZnTiO3 and reduced graphene oxide (rGO) was applied on the surface of the metamaterial. By sintering ZnTiO3 powder at various temperatures, the sensitivity of this device (ΔT/T) was successfully increased from 2% to 16.4%. This material holds promising potential for future developments in monitoring and wearable devices.

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Peripheral blood phosphorylated Tau (p-Tau) protein is one potential biomarker of Alzheimer disease detection. However, the concentration of p-Tau in bloodstream is extremely low (0.09 pg/mL). Tm3+-doped upconversion nanoparticle (Tm3+-UCNP) has fascinating upconversion luminescence (UCL) properties and be utilized to biosensing, usually sub nano-molar level. Here we proposed a low-refractive index resonance waveguide grating (low-RWG) array chip, which integrated 793 nm laser that significantly enhanced Tm3+-UCNP immunosensing to sub femto-molar level. Results showing extremely low limit of detection (LOD) of 0.57 fg/mL. A model study of immunosensor targeting p-Tau181 on the low-n RWG chip is proposed.

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The traditional SPR biosensor uses two-dimensional materials to enhance the sensitivity, but the time is too long to immobilize material enhanced sensitivity on the chip quickly, and a linker is required. Usually linker is a modified functional group between metal and two-dimensional sensing material. The whole process performance is low. In this experiment, graphene is mixed with toner and printed directly on copper foil with a laser printer. The results show that get more obvious character of graphene after printing, which provides a fast and high performance method for immobilized biosensors.

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This study presents a photothermal fiber Fabry–Pérot interferometer (PTFFPI) that is fabricated by a polymer mixed submicron metal particles (PSMP). The proposed PTFFPI-PSMP was heated by a LD with a wavelength of 980nm and an excellent photothermal characteristic was achieved. Based on the experimental results, the device can be successfully heated by laser due to absorption improvement by the polymer mixed metal particles. The LD heating process can achieve a steady-state high temperature (T) to shift the interference wavelength fringes of the PTFFPI-PSMP. Due to the high thermal expansion of polymer, the proposed PTFFPI-PSMP can have a high sensitivity.

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Ultrafast lasers concentrate the energy with a duration of several tens to hundreds of femtoseconds. In practical applications, the optical dispersion broadens the laser pulse width and spreads the energy in time, thereby reducing the peak power. Accordingly, the present study develops a piezo bender-based pulse compressor to compensate for this dispersion effect and restore the laser pulse width. Due to hysteresis and creep effects, the piezo bender is unable to maintain a stable shape over time and the compensation effect is gradually degraded. So, this study further proposes a single-shot modified laterally sampled laser interferometer to solve this problem.

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We developed an ultra-short cavity hollow-core fiber (HCF) Fabry–Pérot Interferometer (HCFFPI) based on splicing a tilted HCF to achieve the measurement of thermo-optic coefficient (TOC) of liquids. Based on fusion splicing an extremely short section (<10um) of slant cleaving HCF between two fibers, a very tiny gap can be formed to ensure that the liquids can flow into the short cavity. The TOCs of DI water, Ethanol, and Cargille liquid (nD=1.33) can be accurately determined by the proposed approach to predict it would have a great advantage for effectively and precisely measuring optical parameters of liquids in picoliters volume.


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In our experiment, we designed a Schottky barrier surface plasmon resonance sensor based on a metal-dielectric-metal structure. The Schottky barrier filters out the noise and improves the sensor design. We established the device fabrication process, including design, debugging, and fabrication, the measurement system, and conducted device testing. Additionally, we analyzed and compared the I-V curves of fabricated and standard samples. Furthermore, the optical characteristics under various incident angles are simulated and measured to demonstrate the surface plasmon resonance (SPR) effects.

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We utilize a semiconductor laser with optical feedback to generate chaos waveforms with broad-bandwidths for lidar applications. By calculating the lags difference through cross-correlation functions, we establish a correlation-based chaos LiDAR system. We study the bandwidth and signal-to-noise ratio and, their impact on the ranging precision. We find that, with the broad-bandwidth waveforms, LiDAR system with higher precision and exceptional anti-interference capabilities can be simultaneously achieved.

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This study introduces a novel step-attached guard ring structure to address edge breakdown effects in InGaAs/InP planar avalanche photodiodes. This innovative approach reduces the edge electric field up to 10.5% and confines breakdown occurrences to the center of the multiplication area.

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A silicon-based device fabricated using Schottky barrier demonstrates that different structural designs modify the surface plasmon resonance, resulting in varying resonance intensity and spatial distribution of the electric field. By hot-carrier diffusion, this device achieves a better infrared light response and amplifies specific wavelength of signals. The device with the newly-designed microstructure exhibits a 2.14-fold enhancement effect with the incident light at 5.3 µm under the same incident light intensities.

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In this paper, we propose a novel fiber optic pressure sensor using a fiber grating
combining with a special packaging structure. Its working principle is based on the fact that
the grating wavelength shift is proportional to the applied pressure, and a fiber grating etching
process is used to increase the sensitivity of the sensor.

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In this work, we prepare cesium lead bromide (CsPbBr3) nanoplatelets (NPLs) by the co-precipitation (CPT) method, which is a simple route to mass-produce nanocrystals under ambient condition. By regulating the molar ration between Cs- and Pb-based precursor, the colloidal CsPbBr3 NPLs are successfully synthesized. Subsequently, the CsPbBr3 NPLs are redispersed in toluene to form a colloidal solution for ultrasonic spray-coating of perovskite film as an X-ray scintillator, whose thickness is well-controlled by the spray-coating cycles. Eventually, a CsPbBr3 perovskite film with a thickness of 553 μm is fabricated to deliver a high X-ray induced radioluminescence.

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Due to the rapid decay characteristics of hot carriers, this study discusses the excitation positions of hot carriers in silicon-based (Si-based) photodetectors to bring the excited carriers closer to the metal/semiconductor interface. This approach aims to increase the injection efficiency of hot carriers, thereby enhancing the responsivity of the photodetector in the mid-infrared (MIR) region.

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